000 02476nab a22003377a 4500
999 _c7104
_d7104
005 20250625151548.0
008 210422s2021 ||||| |||| 00| 0 eng d
040 _aAFVC
100 _aShonkoff, Jack P.
_99941
245 _aEarly childhood adversity, toxic stress, and the impacts of racism on the foundations of health
_cJack P. Shonkoff, Natalie Slopen and David R. Williams
260 _bAnnual Reviews,
_c2021
500 _aAnnual Review of Public Health, 2021, 42: 115-134
520 _aInequalities in health outcomes impose substantial human and economic costs on all societies—and the relation between early adversity and lifelong well-being presents a rich scientific framework for fresh thinking about health promotion and disease prevention broadly, augmented by a deeper focus on how racism influences disparities more specifically. This review begins with an overview of advances in the biology of adversity and resilience through an early childhood lens, followed by an overview of the unique effects of racism on health and a selective review of findings from related intervention research. This article presents a framework for addressing multiple dimensions of the public health challenge—including institutional/structural racism, cultural racism, and interpersonal discrimination—and concludes with the compelling need to protect the developing brain and other biological systems from the physiological disruptions of toxic stress that can undermine the building blocks of optimal health and development in the early childhood period. (Authors' abstract). Record #7104
610 0 _96010
_aCenter on the Developing Child at Harvard University
650 _aADVERSE CHILDHOOD EXPERIENCES
_94089
650 _aCHILD DEVELOPMENT
_9109
650 _aDISCRIMINATION
_93086
650 _aHEALTH
_9283
650 _aINTERVENTION
_9326
650 _aRACISM
_93087
650 _aSTRESS
_9582
651 _aINTERNATIONAL
_93624
651 4 _aUNITED STATES
_92646
700 _aSlopen, Natalie
_99942
700 _aWilliams, David R.
_99943
773 0 _tAnnual Review of Public Health, 2021, 42: 115-134
830 _aAnnual Review of Public Health
_99944
856 _uhttps://doi.org/10.1146/annurev-publhealth-090419-101940
_zDOI:10.1146/annurev-publhealth-090419-101940 (Open access)
856 _uhttps://developingchild.harvard.edu/resources/racism-and-ecd/
_ySee related infographic (includes accessible text)
942 _2ddc
_cARTICLE