000			03344nab a2200397Ia 4500
650	2	7	_9103 _aCHILD ABUSE _2FVC
651	2	4	_aNEW ZEALAND _92588
999			_c2173 _d2173
001			112760
005			20250625151155.0
008			110331s2002 eng
022			_a0003-990X
040			_aWSS _dAFV
100			_aJaffee, S. R. _91425
245			_aDifferences in early childhood risk factors for juvenile-onset and adult-onset depression _cJaffee, S. R.; Caspi, A.; Fombonne, E.; Poulton, R.; Martin, J.
260			_aChicago _bAmerican Medical Association _c2002
365			_a00 _b0
500			_aArchives of General Psychiatry, 2002, 59(3) : 215-222
520			_aThis article discusses a study that examined whether the risk factors for juvenile-onset major depressive disorder (MDD) are different from the risk factors for adult-onset MDD. A representative birth cohort was traced prospectively from birth to age 26 years. The participants were part of the Dunedin Multidisciplinary Health and Development Study. Diagnoses of MDD were made according to the "Diagnostic and Statistical Manual of Mental Disorders" (DSM) (1980, 1987, 1994). Risk factors for early childhood covered the period from birth to 9 years. Diagnoses of MDD were made three times prior to adulthood (ages 11, 13, and 15 years) and three times during adulthood (ages 18, 21, and 26 years). Study members comprised four groups as follows: 21 individuals first diagnosed as having MDD in childhood, but not in adulthood; 314 individuals first diagnosed with MDD in adulthood; 34 individuals first diagnosed in childhood whose depression recurred in adulthood by age 26 years; and 629 individuals who had never been depressed. The results showed that the two groups diagnosed with MDD in childhood had similar high-risk profiles in terms of risk factors. The risk factors for depression included parental characteristics, family circumstances, neurodevelopmental characteristics, and child behaviour and temperament. When compared with the adult-depressed group, the factor of caretaker instability, among others, was experienced more by the juvenile-onset groups. The risk profiles for the adult-onset group and never-depressed group were similar, with the exception that the adult-onset group showed elevated childhood sexual abuse. The author concludes that the distinction between juvenile-onset verses adult-onset MDD is important in understanding the diversity that exists within depression. It is suggested that juvenile-onset MDD may be a distinct subtype that is associated with both genetic and psychosocial risk factors in childhood.
650	2	7	_2FVC _aADOLESCENTS _943
650	2	7	_2FVC _aCHILDREN _9127
650	2	7	_aDunedin Multidisciplinary Health and Development Study _94056
650	2	7	_2FVC _aFAMILIES _9238
650	2	7	_2FVC _aMENTAL HEALTH _9377
650	2	7	_2FVC _aNEGLECT _9401
650	2	7	_2FVC _aSTATISTICS _9575
650	2	7	_9660 _aYOUNG PEOPLE _2FVC
650	2	4	_aSEXUAL VIOLENCE _9531
700	1		_aCaspi, Avshalom _9897
700	1		_aFombonne, E. _91166
700	1		_aPoulton, R. _91936
700	1		_aMartin, Judy _91644
773	0		_tArchives of General Psychiatry, 2002, 59(3): 215-222
830			_aArchives of General Psychiatry _94836
856			_uhttp://dx.doi.org/10.1001/archpsyc.59.3.215 _yRead abstract
942			_2ddc _cARTICLE