Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers A. Danese, T.E. Moffitt H. Harrington, B.J.Milne, G. Polanczyk, C.M. Pariante, R. Poulton, A. Caspi (electronic resource)
Material type:
- 1091-6490
Archives of Pediatric and Adolescent Medicine, 2009, 163(12): 1135-1143
These findings come from a study involving a total of 1037 members of the Dunedin Multidisciplinary Health and Development Study. During their first decade of life, study members were assessed for exposure to 3 adverse psychosocial experiences: socioeconomic disadvantage, maltreatment, and social isolation. At age 32 years, study members were assessed for the presence of 3 age-related-disease risks: major depression, high inflammation levels (high-sensitivity C-reactive protein level >3 mg/L), and the clustering of metabolic risk biomarkers (overweight, high blood pressure, high total cholesterol, low high-density lipoprotein cholesterol, high glycated hemoglobin, and low maximum oxygen consumption levels. From the abstract. Record #3756
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