TY - SER AU - Cochrane, Madeleine AU - Szilassy, Eszter AU - Coope, Caroline AU - Emsley, Elizabeth AU - Johnson, Medina AU - Feder, Gene AU - Barbosa, Estela C. TI - Primary care system-level training and support programme for the secondary prevention of domestic violence and abuse: a cost-effectiveness feasibility model PY - 2024/// PB - BMJ, KW - DOMESTIC VIOLENCE KW - ECONOMIC ASPECTS KW - INTERVENTION KW - HEALTH KW - INTIMATE PARTNER VIOLENCE KW - INTERNATIONAL KW - UNITED KINGDOM N1 - BMJ Open, 2024: 14 :e071300. N2 - Objectives This study aimed to evaluate the prospective cost-effectiveness of the Identification and Referral to Improve Safety plus (IRIS+) intervention compared with usual care using feasibility data derived from seven UK general practice sites. Method A cost–utility analysis was conducted to assess the potential cost-effectiveness of IRIS+, an enhanced model of the UK’s usual care. IRIS+ assisted primary care staff in identifying, documenting and referring not only women, but also men and children who may have experienced domestic violence/abuse as victims, perpetrators or both. A perpetrator group programme was not part of the intervention per se but was linked to the IRIS+ intervention via a referral pathway and signposting. A Markov model was constructed from a societal perspective to estimate mean incremental costs and quality-adjusted life years (QALYs) of IRIS+ compared with to usual care over a 10-year time horizon. Results The IRIS+ intervention saved £92 per patient and produced QALY gains of 0.003. The incremental net monetary benefit was positive (£145) and the IRIS+ intervention was cost-effective in 55% of simulations at a cost-effectiveness threshold of £20 000 per QALY. Conclusion The IRIS+ intervention could be cost-effective or even cost saving from a societal perspective in the UK, though there are large uncertainties, reflected in the confidence intervals and simulation results. (Authors' abstract). Record #8491 UR - https://doi.org/10.1136/bmjopen-2022-071300 ER -