TY - SER AU - Danese, Andrea AU - Moffitt,Terrie E. AU - Harrington,H. AU - Milne,B.J. AU - Polanczyk,G. AU - Pariante,Carmine M. AU - Poulton,Richie AU - Caspi,Avshalom TI - Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers SN - 1091-6490 PY - 2009/// KW - ADVERSE CHILDHOOD EXPERIENCES KW - CHILD EXPOSURE TO VIOLENCE KW - CHILD NEGLECT KW - FVC KW - DEMOGRAPHICS KW - Dunedin Multidisciplinary Health and Development Study KW - HEALTH KW - MENTAL HEALTH KW - SOCIOECONOMIC FACTORS KW - CHILD ABUSE KW - NEW ZEALAND N1 - Archives of Pediatric and Adolescent Medicine, 2009, 163(12): 1135-1143; xxu N2 - These findings come from a study involving a total of 1037 members of the Dunedin Multidisciplinary Health and Development Study. During their first decade of life, study members were assessed for exposure to 3 adverse psychosocial experiences: socioeconomic disadvantage, maltreatment, and social isolation. At age 32 years, study members were assessed for the presence of 3 age-related-disease risks: major depression, high inflammation levels (high-sensitivity C-reactive protein level >3 mg/L), and the clustering of metabolic risk biomarkers (overweight, high blood pressure, high total cholesterol, low high-density lipoprotein cholesterol, high glycated hemoglobin, and low maximum oxygen consumption levels. From the abstract. Record #3756 UR - http://www.ncbi.nlm.nih.gov/pubmed/19996051 ER -